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What is ccnd1 gene

Complete information for CCND1 gene (Protein Coding), Cyclin D1, including: function, proteins, disorders, pathways, orthologs, and expression. GeneCards. This protein has been shown to interact with tumor suppressor protein Rb and the expression of this gene is regulated positively by Rb. Mutations, amplification. 2 days ago The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in.

Cyclin D1 is a protein that in humans is encoded by the CCND1 gene. Contents. 1 Gene expression; 2 Protein structure; 3 Function. Normal function; CCND1/PTH FUSION GENE, INCLUDED CCND1/IGLC1 FUSION GENE, INCLUDED CCND1/FSTL3 FUSION GENE, INCLUDED. HGNC Approved Gene . Translocation t(11;14)(q13;q32) with immunoglobulin gene regions. Activation of CCND1 may be oncogenic by directly altering progression through the cell.

CCND1 (cyclin D1) is a protein-coding gene. Diseases associated with CCND1 include superficial urinary bladder cancer, and breast papillary carcinoma. Description, Located in the long (q) arm of chromosome 11 in the 13th band, the length of the CCND 1 gene is about Kb (precisely 13, bases). Although increasingly recognized in other lymphoproliferative disorders, cyclin D1 expression and CCND1 gene abnormalities have not been. In summary, our data implicate that despite a significant correlation to cyclin D1 protein expression, amplification status of the CCND1 gene seems a strong.

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